Profhilo

While both treatments are made from Hyaluronic Acid (HA), Profhilo® and dermal fillers serve completely opposite clinical functions. Traditional fillers use chemical agents (like BDDE) to cross-link the HA into a dense, structural gel designed to stay exactly where it is placed to add artificial volume or shape. Profhilo®, however, is completely free from BDDE or chemical additives. It is created using a unique thermal cross-linking process, combining high- and low-molecular-weight HA into an ultra-pure, honey-like fluid. Instead of plumping an isolated line, Profhilo® flows smoothly across the tissue layers, triggering widespread cell hydration and dynamic tissue remodeling without altering your natural facial geometry.

At our doctor-led Mapperley clinic, we administer Profhilo® using the internationally standardised BAP (Bio Aesthetic Points) technique. This method involves mapping out exactly 5 specific injection points on each side of the face: the zygomatic (high cheekbone), nasal base (alar), pre-auricular (in front of the ear), chin, and mandibular angle (jawline corner). These points are carefully chosen because they avoid major blood vessels and lie directly above the skin's natural lymphatic drainage channels. Because of Profhilo's exceptional fluid rheology, injecting a precise dose into these 5 localised depots allows the product to smoothly diffuse over a 2cm radius, treating the entire mid-and-lower face uniformly while minimising the risk of bruising.

A foundational Profhilo® protocol requires 2 initial treatment sessions, spaced exactly 4 weeks apart. Because it relies on slow cellular bio-remodeling rather than a synthetic physical gel, your results accumulate gradually over time. While an initial wave of deep dermal hydration can be seen within the first week—manifesting as a healthy skin glow—the true transformation happens beneath the surface. Over the 8 weeks following your first session, the pure HA microparticles continuously stimulate your native skin receptors, triggering cellular angiogenesis (increased blood flow) and ramping up production of 4 distinct types of collagen and elastin. Your final, optimized skin firmness and elasticity are reached roughly one month after your second session.

Yes, seeing small, raised bumps at the exact injection sites is a completely normal, expected physiological response. Because the BAP technique places a localised fluid depot just beneath the skin surface, these small blebs can look like tiny bee stings immediately after treatment. You must not massage or press these bumps, as doing so interferes with the product's natural diffusion pathway. Thanks to Profhilo's high fluid mobility, these depots naturally flatten and dissolve completely into the surrounding tissue layers within 24 to 48 hours as the skin absorbs the pure moisture.

After completing your initial two-part foundational course, the visible improvements in skin quality, bounce, and fine-line smoothing typically last for 6 to 9 months. The treatment naturally degrades without leaving any residue behind. To continuously combat the natural drop in your body's structural proteins and maintain a radiant, firm complexion, we recommend booking a single maintenance session every 6 months.